Application: Amebiasis, trichomoniasis, giardiazis, giardiasis, intraabdominale infection (peritonitis, abscess), anaerobic infection bones and joints, and skin and soft tissues, female genitals (dysmenorrhea, tuboovarialny abscess), central nervous system (meningitis, brain abscess), lower respiratory tract infections (pneumonia, empyema, lung abscess), endocarditis, psevdomembranosny colitis, eradikation Helicobacter pylori, chronic alcoholism, the prevention of postoperative anaerobic infections. For external and local application: pink and vulgar acne, bacterial waginozy on the long-term healing wounds, trophic ulcers.
Contraindications: Hypersensitivity (including from other derivative of nytroimidazole.), Pregnancy, breast-feeding (at the time of treatment must stop breastfeeding), children's age (except in the case of amebiasis).

Limitations to the application of: liver Disease in violation of its functions (possible accumulation), the central and peripheral nervous system.

Side effects: Nausea, vomiting, pain in the abdomen, diarrhoea, unpleasant metallic taste, headache, dizziness, syncope status, ataxia, the violation of consciousness, seizures, neutropenia (leukopenia), eritematosnye skin, itchy skin, staining of urine in a dark color, allergic reactions, throm (after the / in the introduction).

Interactions: do indirect effects anticoagulants and lithium salts. Phenytoin and phenobarbital reduce the (due to the activation of microsomal system of the liver and speed up the metabolism and excretion), and increases zimetidin (inhibits the enzyme system of the liver and, as a result, slows down biotransformatia). Incompatible with alcohol (with the joint admission develops antabuspodobny syndrome).

Overdose: Symptoms: nausea, vomiting, ataxia, in the most severe cases, peripheral neuropathy and epileptic seizures. Treatment: symptomatic; specific antidote is not available.

Way of administration and dosage: Inside, during or after a meal. Amebiaz: adults on the 800 mg three times a day for 10 days; children 35-50 mg / kg / day in 3 admission for 8-10 days. Giardiazis: 15 mg / kg / day in 3 admission within five days. Trichomoniasis: adult - inside, 400 mg twice a day for 5 to 8 days (if necessary re-training through the 4-6 weeks) once or 2.0 g or 250 mg twice a day for 10 days; is carried out simultaneous treatment of both partners. Children: 2-5 years, 250 mg / day, 5-10 years, 250-375 mg / day, over 10 years - 500 mg / day orally, the daily dose is divided into three reception. Giardiasis: adults - 400 mg three times a day for 5 days or on the 250 mg twice a day for 10 days; children: 2-5 years, 250 mg / day, 5-10 years, 250-375 mg / day, over 10 years - 500 mg / day orally, in 3 admission. After completion of treatment in 2-3 months is a follow-up study on the completeness of healing. Eradikation Helicobacter pylori: 500 mg three times a day for 7 days, always in combination with other drugs. Anaerobic infection: adults - 400 mg three times a day for 7 to 10 days; children up to 12 years in the 7.5 mg / kg three times a day. In severe cases, the drug being dropped (in / in drip) adult 500 mg in 100 ml of solvent, children at the rate of 7.5 mg / kg in the same quantity of solvent. Infuziu a quick 5 ml / min intervals of eight hours. For the prevention of postoperative anaerobic infections: in the 1-th day after operation, 1 g of the drug once, in the future in the 200 mg three times a day for 7 days. Chronic alcoholism: inside, in the 0.5 g / day for 6 (not more) months. Intrawaginalno: 500 mg per night for 10 days. Externally: used 2 times a day, the dose is determined individually.

Trade names of drugs with the active ingredient Metronidazole * (Metronidazole) *

Akvametro (Aquametro) Metronidazole Vathem Rozamet (Rosamet) Apo-Metronidazole (Apo-Metronidazole) Metronidazole Nycomed (Metronidazole Nycomed) Rozeks Klion (Klion) Metronidazole-ACOS (Metronidazol-ICCO) Trihazol (Trichazol) Metrogyl Metronidazole-Ros (Metronidazol-Ros) Trihobrol (Trichobrol) Metrozol (Metrozol) Metronidazole-Rusfar (Metronidazol-Rusphar) Trichopolum (Trichopol) Metrolaker (Metrolacare) Metronidazole-TAT Flags (Flagyl) Metron (Metron) Metronidazole-Teva (Metronidazole-Teva) Efloran (Efloran) Metronidazole (Metronidazol ) Metronidazole-Farkos (Metronidazol-Farkos Metronidazole) in / in Brown (Metronidazole iv Braun) Metronidazole tablets 0.25 g (Tabulettae Metronidazoli 0.25 g)